Advanced Cardiac Therapeutics Announces Presentations at 2012 Heart Rhythm Society Meeting

MENLO PARK, Calif., May 7, 2012 – Advanced Cardiac Therapeutics, Inc., a developer ofinnovative temperature-sensing cardiac ablation systems, today announced several presentationsrelated to the company’s TEMPASURE™ cardiac ablation catheter at the Heart Rhythm Society's33rd Annual Scientific Sessions. The Heart Rhythm Society conference takes place at the BostonConvention and Exhibition Center May 9-12, 2012 in Boston, Mass.

The TEMPASURE system is designed to improve clinical outcomes by providingelectrophysiologists with real-time validation information and greater control in lesion creation forthe treatment of patients with cardiac arrhythmias.

Three presentations on Thursday May 10 will feature the TEMPASURE system:

• Vivek Reddy, M.D., of Mt. Sinai School of Medicine in New York will deliver an oralpresentation titled “Tissue Temperature Sensing During Irrigated Radio FrequencyAblation: A Novel Strategy To Predict Steam Pops” at 1:45 p.m. ET in Room 205A.
• Hiroshi Nakagawa, M.D., Ph.D., of the University of Oklahoma Health Sciences Centerwill present “Microwave Volumetric Temperature Sensor Improves Control Of RadioFrequency Lesion Formation And Steam Pops” at 2:30 p.m. ET in Room 204B.
• Dr. Nakagawa will present a poster titled “Novel Irrigated Radio Frequency AblationCatheter With Microwave Volumetric Temperature Sensor Predicts Lesion Size AndIncidence of Steam Pops” from 2:00 to 5:00 p.m. ET in the Exhibit Hall.

About Cardiac Arrhythmias
Cardiac arrhythmias occur when the electrical impulses in the heart don't work properly, causingthe heart to beat too fast, too slowly or irregularly. Atrial fibrillation and atrial flutter are fastcardiac arrhythmias that are the leading cause of stroke and can be life-threatening.

About Cardiac Catheter Ablation
Cardiac catheter ablation procedures are used to treat a variety of cardiac arrhythmias includingatrial fibrillation and atrial flutter. The procedures involve advancing a catheter into the heart andselectively ablating certain areas of tissue in order to prevent the spread of electrical signals thatgive rise to the arrhythmia. The temperature of the tissue during ablation is critical – lowertemperatures are ineffective, and temperatures that are too high can result in dangerous overheating.Saline irrigation ensures that lesions are created safely and are effective deeper insidethe cardiac tissue. However, the inclusion of irrigation negates the effectiveness of conventionalthermometry.

About the TEMPASURE Cardiac Ablation Catheter
The TEMPASURE system is designed to improve patient outcomes of cardiac ablationprocedures by providing electrophysiologists with real-time validation information and greatercontrol in lesion creation. The system’s novel passive sensing microwave radiometry technologyallows the electrophysiologist to measure the temperature of cardiac tissue during the ablationprocedure, providing real-time information that enables proper energy delivery and lesion control.This technology enables, for the first time, measurement of tissue temperature with a salineirrigatedRF catheter.

About Advanced Cardiac Therapeutics
Headquartered in Menlo Park, Calif., privately held Advanced Cardiac Therapeutics, Inc.specializes in advanced irrigated cardiac catheter ablation systems with proprietary temperaturesensingtechnology for the treatment of patients with cardiac arrhythmias. For more informationvisit www.actmed.net.